Holding(s) in Company

02/02/2007

TR-1(i): NOTIFICATION OF MAJOR INTEREST IN SHARES

1. Identity of the issuer or the underlying issuer of existing shares to which voting rights are attached (ii):

ReGen Therapeutics Plc

2. Reason for the notification:

An acquisition or disposal of voting rights

3. Full name of person(s) subject to the notification obligation (iii):

Barclays PLC

4. Full name of shareholder(s) (if difference from 3):

Barclays Stockbrokers Ltd
Gerrard Ltd

5. Date of the transaction and date on which the threshold is crossed or reached (v):

24 January 2007

6. Date on which issued notified:

1 February 2007

7. Threshold(s) that is/are crossed or reached:

6%

8. Notified details

A: Voting rights attached to shares

Class/type of share if possible using the ISIN Code GB0004468319

Situation Previous to the triggering transaction (vi) -
Number of Shares 41,468,724
Number of Voting Rights (viii) 41,468,724

Resulting situation after the triggering transaction (viii) -
Number of Shares 41,868,724
Number of Voting Rights – Direct (x) N/A
Number of Voting Rights – Indirect (xi) 41,868,724
% of voting rights – Direct N/A
% of voting rights – Indirect 6.03

B: Financial Instruments

Resulting situation after the triggering transaction (xii)

Type of financial instrument N/A

Expiration date (xiii) N/A

Exercise/Conversion Period/Date (xiv) N/A

Number of voting rights that may be acquired if the
instrument is exercised/converted N/A

% of voting rights N/A

Total (A+B)

Number of voting rights 41,868,724

% of voting rights 6.03

9. Chain of controlled undertakings through which the voting rights and/or the financial instruments are
effectively held, if applicable (xv):

Barclays Stockbrokers Ltd
Gerrard Ltd

Proxy Voting:

10. Name of the proxy holder: N/A

11. Number of voting rights proxy holder will cease to hold: N/A

12. Date on which proxy holder will cease to hold voting rights: N/A

13. Additional information: N/A

14. Contact name: N/A

15. Contact telephone number: N/A

N/A

For further information:

Andrew Marshall

Greycoat Communications

Tel: +44 (0) 207 960 6007

Mobile: +44 (0) 7785 297111

Imran Ahmad / Rod Venables/ Cecil Jordaan

HB-Corporate

Tel: +44(0) 207 510 8600