Share Issue

18/12/2001

London, UK – 18 December 2001: ReGen Therapeutics Plc (the ‘Company’), a company developing a potential treatment for Alzheimer’s disease, announces that it has today issued 399,000 new ordinary shares to existing shareholders at 10p per share (‘New Ordinary Shares’). The issue of the New Ordinary Shares has been made pursuant to the existing general authority given to Directors at the Extraordinary General Meeting of the Company held on 5 November 2001.

Application has been made for the New Ordinary Shares to be admitted to the Alternative Investment Market of the London Stock Exchange plc and dealings are expected to commence at 8.00 am on 21 December 2001.

For further information, please contact:

Buchanan Communications
Lisa Baderoon
Tel No: 020 7466 5000
Mobile: 07721 413496
lisab@buchanan.uk.com